Non-targeted, unlabeled, high-resolution spatial mapping – benchmarks of the new era of next-generation mass spectrometry imaging technologies.
In recent years, huge steps have been made to standardize and manufacture equipment for 3D cell culture—making it cheaper, simpler and more reproducible.
New microplate products are bringing techniques such as confocal microscopy out of imaging and screening facilities and into the realm of basic research labs and their applications.
As imaging technologies continue to forge ahead, a few areas in particular promise to make for an interesting year and offer extraordinary vision for what is to come.
These trends may enable more complete biomarker panel validation, greater coverage in complex metabolomics areas such as lipidomics, and ultra high-resolution imaging of complex tissues such as brain.
The annual meeting of the Society for Neuroscience is a humbling experience. The electrifying hum of high-minded neuro-speak echoes among the attendees – over 30,000 strong. A resounding topic of discussion this year included new imaging technologies and the insight these may provide into complex brain processes.
In addition to the proliferation of microplate imaging technologies, antibodies and immunoreagents have become invaluable in many advanced cell biological and physiological research areas -- such as high-resolution imaging and super-resolution microscopy.
Modern technologies strive to remove variability in staining, sample transfer, and the influence of the user. Here we detail a few advanced systems.