Mass Spec Matters
Several new FDA-approved tests based upon mass spectrometry showcase the power of mass spec not only as a discovery tool, but as a platform for emerging public health challenges of immediate importance.
Mass spectrometry once again wields its might, combating the COVID-19 pandemic from multiple aspects. Here is a brief look at some of the method development and collaborative efforts that are leading the charge.
The purely digital “reboot” format for the conference this year made for an outstanding experience, rich with interactive, on-demand, and downloadable content -- in addition to some electrifying new product buzz.
Research into SARS-CoV-2 spike protein and other areas are contributing to the development of viable vaccines, drugs, and therapeutic antibodies -- all benefiting from new glycan analysis and LC-MS solutions.
New and emerging supercritical fluid chromatography applications have brought with them a host of new technologies -- with elevated performance, efficiency, and green chemistry as key drivers.
The new decade holds both promise and remaining challenges for widespread adoption of mass spectrometry in the clinical lab
Non-targeted, unlabeled, high-resolution spatial mapping – benchmarks of the new era of next-generation mass spectrometry imaging technologies.
Modern food safety and testing employs state-of-the-art mass spec methods and technologies for applications in import screening, domestic profiling, and many other important areas of food science.
As the concept matures, next-generation proteomics promises to usher in a new layer of insight to complement NGS in the realization of true precision medicine. Advanced technologies showcased at the American Society for Mass Spectrometry annual meeting offer progress towards this goal.
Here we highlight a few new HPLC/UHPLC instrument platforms -- those which offer superior flexibility and performance for today’s unique analytical challenges.
Ion Mobility Mass Spectrometry offers a unique layer of separations power and adds yet another dimension for complex, high-throughput applications.
The “smart” laboratory trend has now expanded to include “intelligent” high-end analytical devices – aiming to increase workflow efficiencies and instrument productivity -- while reducing costs and instrument downtime.
These trends may enable more complete biomarker panel validation, greater coverage in complex metabolomics areas such as lipidomics, and ultra high-resolution imaging of complex tissues such as brain.
We detail some of the fundamentals of liquid chromatography and examine emerging trends and new products -- with special focus on nanoflow and chip-based technologies.