Spectrophotometers measure intrinsic properties of materials, compounds, proteins, by measuring absorbance and/or emission of ultraviolet, visible (UV/Vis) or fluorescence (Fluor) light. There are many platforms available depending on the material to be analyzed and the methods required. Instrument calibration features and source drift are important details to watch for in choosing a new or used device. Multiwavelength reading and scanning capabilities are notable features as well. Advanced features such as methods programming, data storage, and connectivity are more common on modern devices. Data tracking and monitoring can be useful for validated methods and clinical applications.