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Save up to 75% off Lab EssentialsFind laboratory equipment and accessories up to 75% off the list price during our BUCHI ...

Are you looking for a solution to improve air monitoring to minimize contaminants in your lab?Does your lab suffer from the burden of costs and resources to maintain compliance?Biosafety Cabinets (BSCs) provide a clean,...

The Thermo Scientific™ NanoDrop™ Eight Spectrophotometer builds on the NanoDrop 8000 -  the original high-throughput NanoDrop instrument - and our flagship NanoDrop One/OneC Microvolume UV-Vis Spectropho...

Modern molecular techniques rely on reliable quantities of DNA or RNA. Accurate quantitation of nucleic acids is critical for applications including molecular cloning, next gen sequencing, ligation, PCR, transfec...

The determination of organic carbon plays a fundamental role in the characterization of soils and sediments.  Total organic carbon (TOC) analysis is indispensible in assessing soil health and fertility by indicating the ...

PFAS contamination is a growing global problem with severe environmental and health implications. Regardless of the sources, measures must be taken to accurately detect and mitigate the buildup of PFAS chemicals in the en...

The CellXpress.ai Automated Cell Culture System is a groundbreaking solution for scaling up drug discovery and addressing the challenges of traditional induced pluripotent stem cell (iPSC) culturing. This innova...

Since the launch of the Orbitrap Astral system at the 2023 ASMS conference, pivotal developments ranging from increased single-cell sensitivity and resolution to expanded quantitation and throughput have propelled the fields ...

FTIR analysis has long been an integral part in quality assurance (QA) and quality control (QC) in many industries, from pharmaceuticals, food & beverages, and cosmetics to polymers and other chemicals. Typic...

The growth in popularity and acceptance of Fourier transform infrared (FTIR) spectrometers for use in quality assurance (QA) laboratories and on manufacturing floors is one of the major developments affecting ind...

Immuno-oncology represents a transformative approach to cancer treatment, harnessing the power of the immune system to fight cancer. Our Immuno-oncology Product Resource Guide is your essential companion in this rapidly evolv...

Lab sustainability goes beyond fume hoods and cold storage—benchtop equipment can significantly influence a lab’s environmental footprint.Why It MattersBenchtop instruments like balances are dai...

Faster, safer, and more reliable analysis of volatile organic compounds (VOCs) in drinking and surface waterEnvironmental agencies worldwide strictly regulate volatile organic compounds due to ...

During drug and biotherapeutic development, the ability to measure binding activities between biomolecules is often critical. Such interaction assays serve an important role in screening, antibody structure analy...

Our goal is to support your immuno-oncology research with a comprehensive range of tools and technologies that maximize your time, budget, and data—helping to accelerate your path to discovery and translation to a c...

Looking to unlock additional insights into biology and disease mechanisms? With faster throughput, deeper coverage, higher sensitivity, and accurate and precise quantitation; the Thermo Scientific Orbitrap Astral Mass Spectro...

In our Going Green Whitepaper, discover six exciting research projects that are helping us to understand and reduce environmental water contaminants. We discuss the consequences of environmental water contaminants, including ...

GPCRs are notoriously difficult to study due to their intrinsic protein instability. By utilizing the sensitivity of Grating Coupled Interferometry (GCI) technology combined with non-clog microfluidics, these pesky membrane p...

Ensuring your equipment investment aligns with your lab’s long-term success Purchasing lab equipment is a critical investment, and choosing the right source is key to ensuring quality, reliability, an...

In many CHO fed-batch approaches, the cell culture media, basal, and feed, are designed to supply enough nutrients for the majority of cell lines, but overfeeding may lead to the accumulation of toxic metabo...

Monitoring and control of critical process parameters (CPPs) such as glucose and lactate are essential to maintaining optimal cell culture conditions, which includes ensuring product quality and maximizing yield...

This study explores the relationship between CAR T-cell activation, nutrient metabolism, and treatment efficacy. It highlights differences in amino acid (AA) concentrations in spent media between potent CAR T-ce...

Gas chromatography is a separation technique widely used in many analytical testing and research laboratories to unravel samples composition or quantify impurities. It is a key analytical tool fo...

Biomolecular imaging tools, designed for the precise quantification of proteins, nucleic acids, and other biomolecules, play a critical role in all areas of life sciences. Imaging tools enable researchers to explore cellu...

As atomic spectroscopy techniques for elemental analysis have advanced over the years, the need for better sample preparation has grown. While digestion is often the focal point, other steps in the sample preparation workflow can...

How does your lab establish best practices for pipetting? How can you ensure proper training when onboarding new staff? How can your lab stay current with updates to regulations and compliance? Pi...

Understanding the physiological state – or health – of your cells is the first step toward experimental success during drug research. Cell stress, apoptosis, necrosis, autophagy, and metabolic changes...

This guide contains step-by-step instructions for common imaging protocols, including tips for a successful experiment, and lists of needed supplies. Essential protocols include:Cell proliferationCell viabili...

Mass spectrometry has a long and celebrated history as a foundational technique in biochemistry. Itsability to cleave molecules into charged fragments, then sort those fragments according to their mass-to-charge...

Stepping into the Thermo Fisher Scientific hospitality suite at the American Society for  Mass Spectrometry (ASMS) annual conference was like being transported into the future. Beyond the three dimensions of space, time appe...

Pharmaceutical development is a complex, resource intensive process that demands the latest technologies and solutions to provide the best chances at success.The discovery process requires high-quality...

Get to know how capillary electrophoresis enables a variety of applications for a broad range of research areas through Sanger sequencing and fragment analysis.Sanger sequencing, the gold standard of sequencing, provides...

Water testing includes everything from routine drinking water screenings to targeted safety investigations following a Legionella outbreak. Regardless of the sample, water testing laboratories have the dual aim of obtaining r...

For over four decades, microplate readers have been indispensable in scientific research, driving advances in protein and cell biology. When researchers choose a microplate reader, they are investing in technolo...

What should I consider when selecting tubes for cryopreservation? How do I choose the best tubes for automated liquid handling? Is compatibility a big concern when it comes to solvent-based samples? ...

Axcend’s revolutionary line-up of eco-friendly, compact and portable HPLC instruments and accessories are engineered to deliver consistent, high-quality performance, ensuring precise and dependable analyti...

The quality of DNA samples is critical to the success of next-generation sequencing (NGS) workflows. This study examines how using a DNA Integrity Number (DIN)- based threshold can optimize sequencing by assessin...

Short synthetic oligonucleotides, such as small interfering RNA, antisense oligonucleotides, aptamers, and CRISPR guides have gained much attention and grown rapidly as a new type of drug in gene therapy. The suc...

Sorting very large cells with standard nozzle tip sizes on cell sorting flow cytometers can be challenging. This is primarily due to the scarce frequency of large cells and their fragile nature. The required pressures for 70,...

Protein purification is an essential process in advancing protein science, disease research, and therapeutic discovery. Filtering impurities and cell debris is critical for maintaining the accuracy and reproducibi...

“There are many factors to consider when selecting the proper rotary evaporator. Details including temperature control, batch size, and throughput requirements will help determine the best system for your lab.” - ...

From Sample to Separation to Analysis—All in One Visual Guide Are you optimizing your oligo synthesis process? Whether you're analyzing target sequences or detecting impurities, having the right tools an...

Learn how energy dispersive X-ray fluorescence (EDXRF) is being used across academia, pharmaceuticals, and mining to deliver fast, non-destructive, and accurate elemental analysis This exclusive compilation of applicat...

From particle size to zeta potential, molecular weight to microrheology—analyze it all with a single powerful instrument. The BeNano 180 Zeta Max by Bettersize Instruments delivers unmatched versatility and precision ac...

How does your lab establish best practices for pipetting?How can you ensure proper training when onboarding new staff?How can your lab stay current with updates to regulations and compliance?Pipetting is a universal technique...

PFAS contamination is a growing global problem with severe environmental and health implications. Regardless of the sources, measures must be taken to accurately detect and mitigate the buildup of PFAS chemicals in the enviro...

Bioanalytical labs need reliable tools to deliver accurate results and meet tight drug discovery and development timelines. Downtime from less robust instruments can disrupt workflows, making durable and dependable systems es...

Purchasing laboratory equipment often involves long lead times, stock shortages, and uncertainty, causing delays in critical projects. These challenges are particularly pressing when labs are under tight timelines for set up ...

Mammalian cell culture for cell line development is a cornerstone of biomedical research and therapeutic production. However, this process presents significant challenges, including the need for stringent control...

Elemental analysis demands precision, speed, and safety. Traditional sample preparation techniques like hot plates and heating blocks simply can’t keep pace with today’s laboratory needs. That’s why microwav...

The development of three-dimensional (3D) organoids marks a pivotal advancement in drug discovery and biomedical research. These structures, capable of self-organizing and mimicking the functionality of human organ ce...

“It’s important to consider what you going to be doing with the instrument. Are you going to be using it for multiple different applications, or is it just a targeted application that you're looking f...

This essential guide explores complementary measurement methods to address a range of quality control applications, ensuring reliable data across diverse sample types. Key Solutions ...

Quality control (QC) labs are at the forefront of ensuring product safety and efficacy, particularly in industries such as pharmaceuticals and biotechnology. These labs face mounting challenges, including stringent regulatory...

Sterility testing is a critical process to ensure that pharmaceuticals and medical devices remain free from viable contaminating microorganisms before release. This comprehensive guide addresses the challenges and provides step-b...

Achieving accurate weighing results relies heavily on maintaining clean laboratory balances, as contamination can compromise data integrity. Despite its importance, challenges persist including how to effectively address spil...

Analyzing synthetic oligonucleotides presents unique challenges due to their complex structures and modifications, such as phosphorothioate linkages and ribose alterations. These features can cause difficulties like band broa...

Multiplex live cell imaging enables the observation of multiple cellular structures and processes simultaneously, offering a more physiologically relevant understanding of dynamic interactions. However, the approach presents ...

Single-cell RNA sequencing (scRNA-Seq) and single-cell ATAC sequencing (scATAC-Seq) rely on precise single-cell counts to generate high-quality data. However, accurate enumeration is challenging due to the presence of cellula...

Effective blood separation is crucial for accurate point-of-care diagnostic testing using whole blood. However, the complexity of blood—comprising red and white blood cells, platelets, and plasma—poses challenges ...

Laboratory shaking incubators are essential instruments for applications requiring precise temperature control and agitation, such as microbial growth, cell culture, and protein expression. However, their complex components&m...

Cell-based models are essential for drug development and biological research. However, traditional tissue culture remains one of the most labor-intensive and error-prone aspects of laboratory work. Complex protoc...

Did you know that in some cases, using fewer antibodies can result in more signal? Or, conversely, that using more antibody can result in less signal?A dot blot is a simplified version of a western blot that is performed to o...

Spatial imaging is transforming how researchers understand biological complexity by visualizing the spatial distribution of biomolecules within tissue samples. To support scientists in extracting deeper insights from a si...

Controlled environment testing is critical across industries where product stability, safety, and regulatory compliance are paramount. Stability chambers are precision- engineered units that maintain consistent temperature an...

Boost productivity. Cut costs. Minimize environmental impact.Is your lab still running outdated HPLC methods that waste time, money, and resources? Modernizing your approach doesn’t have to be complicated. In this free ...

 Making the choice to replace or upgrade your mass spectrometer is an important decision. With multiple options available for buying new or pre-owned instruments, it’s important to know what to consider when ev...

Laboratory balances are essential tools for applications ranging from pharmaceutical formulation to routine sample prep. However, achieving accurate, reproducible results is not always straightforward. Lab professionals often...

Manual solvent handling isn’t just time-consuming, it’s risky. Automating solvent transfer using the Hei-VOLUME Pro minimizes operator exposure and extends operational hours without human intervention. The Hei...

Tumor protein p53 plays a pivotal role in regulating cell health—yet mutations in the p53 gene are implicated in nearly 50% of all cancers. In this application note, researchers used the Therm...

The semiconductor industry is advancing at breakneck speed—pushing for faster, smaller, and more powerful devices. From 5G and AI to electric vehicles and advanced medical technologies, success depends on the precision ...

Choosing the right lab balance is more than a purchase—it’s an investment in accuracy, efficiency, and long-term success. “There are many factors which come into play considering buying a balance. Sta...

Pharmaceutical and biotech labs operating under FDA and EU GMP requirements must meet stringent standards for electronic records and electronic signatures. This white paper from Sartorius offers a comprehensive c...

In a lab environment where every degree matters, selecting the right refrigerator, freezer, or incubator can mean the difference between experimental success and costly setbacks. But how do you evaluate performance metrics that a...

Whether you’re advancing microbiome studies, engineering microbial strains, or pioneering synthetic biology research, traditional colony picking workflows can be bottlenecks to success. Challenges include: •...

This free eBook offers practical strategies and expert insights to streamline and strengthen your lab’s operations. Whether you're analyzing air, water, soil, or waste, sample prep is often the most time-consuming p...

“When selecting microcentrifuge tubes, it’s vital to consider factors beyond basic specifications. Today’s lab professionals must balance sample protection with workflow efficiency, regulatory compliance, an...

Are you looking to reduce solvent use, operating costs, and lab footprint—while still meeting USP method compliance?This application note, authored by Sam Foster and Milton Lee, demonstrates how to successfully adapt a ...

Agilent’s innovative LC and LC/MS column chemistries are designed to streamline oligo analysis—from discovery through scale-up—ensuring optimal resolution, recovery, and throughput.In this free, easy-to-digest i...

ISO 8655:2022 Part 10 introduces critical updates for establishing and maintaining a pipetting workflow that meets international compliance standards. This free infographic breaks down exactly what your lab needs to know ...

Whether you're new to enzyme-linked immunosorbent assays (ELISAs) or managing high-throughput projects, inconsistent results can compromise your data. This eBook is your go-to reference for enhancing accuracy, re...

Modern labs demand more than basic imaging. Whether you're working with multi-well plates, live-cell cultures, or time-lapse experiments, traditional fluorescence microscopes often can't keep up.The EVOS M7000 Ima...

This application note explores a comprehensive, ISO 10694-aligned method for accurate TOC determination using the LECO C832 combustion analyzer. Guidance covers precise sample preparation, acid digestion, and com...

As the demand for faster, more flexible analytical workflows grows, compact gas chromatography (GC) systems are emerging as the solution of choice for modern labs. This whitepaper—The Rise of Compact Yet Cap...

The ability to generate clear and detailed publication-quality microscopy images is critical to your success, particularly in today’s competitive scientific environment This infographic demonstr...

Selecting the right microscope requires careful evaluation of your imaging needs, available features, and budget. Whether you are conducting routine lab work or high-end research, understanding the key factors ca...

Accelerate compliance screening with a practical, lab-ready workflow for total organic fluorine (TOF) in paper, fiber, and other food contact materials State restrictions on PFAS in food packaging are expanding...

Immunodiagnostics is transforming modern healthcare. From disease detection to therapeutic monitoring, accurate and reliable immunoassays are central to advancing diagnostics. Now, with the integration of magneti...

Molecular diagnostics is transforming healthcare, with fast, precise tests for everything from infectious diseases to complex genetic disorders. At the core of these breakthroughs lies a critical step: nucleic ac...

Cement production accounts for approximately 8% of global CO₂ emissions, making innovation in this sector vital to global decarbonization efforts. This eBook, Cementing Sustainability with Materials Analys...

Protein detection and quantification are at the heart of life science and biomedical research. But with so many imaging systems on the market, selecting the right one for your workflow can be challenging. This eB...

Halogens and sulfur play a critical role in industrial processes and environmental health. Their presence can impact product quality, equipment integrity, and regulatory compliance—from corrosion in refiner...

Labs are under constant pressure to process more samples, ensure compliance, and deliver defensible data, all while cutting costs and protecting staff. Instrumentation continues to advance, but sample ...

Per- and polyfluoroalkyl substances (PFAS) are among the most pressing environmental challenges of our time. With more than 14,000 synthetic fluorinated compounds in use across consumer products, industrial proce...

When it comes to qPCR, instrument performance is only part of the equation. The real driver of efficiency, accuracy, and cost-effectiveness lies in the software that powers your workflows. This eBook from Bio-Rad...

Automated liquid handlers are essential in today’s laboratories, driving throughput, accuracy, and consistency across genomics, diagnostics, and drug discovery. But acquiring one new can be a significant ca...

Microbiome research is transforming our understanding of health, disease, and the environment. But traditional manual techniques—colony picking, plating, liquid handling, and streaking—are often slow, ...

Laboratory safety cabinets are more than protective enclosures—they are the backbone of biosafety, productivity, and compliance. Updating to a new BSC system will help you improve processes and stay ahead of...

Mutations in the ESR1 gene are a leading cause of resistance to endocrine therapy in estrogen receptor–positive breast cancer. Detecting these variants early is critical for advancing clinical research and d...

Capillary electrophoresis has long been valued for its precision, speed, and versatility. Today, it continues to play a critical role in advancing clinical diagnostics—from identifying genetic variants to c...

As research in biopharma, proteomics, and metabolomics continues to expand, so do the challenges of analyzing complex molecules, detecting subtle variants, and achieving accurate quantification. The Orbitrap Exce...

As industries shift toward a circular economy, achieving sustainability in polymer design and recycling has become more urgent than ever. This whitepaper from Thermo Fisher Scientific highlights how small-scale e...