Overview

Gator Bio™ has recently launched the SMAP (Small Molecule, Antibody, and Protein; Cat # 160011) biosensor. As other Gator Bio biosensors, SMAP has fundamental physical and chemical design elements that provide much higher sensitivity. This biosensor has best in class BLI sensitivity for small molecules (down to 150 Da) that gets close to SPR sensitivity. It is the only BLI biosensor on the market that performs extremely well in peptide-antibodies kinetic studies. It can also be used for protein and antibodies. Compatible with our Gator and GatorPlus instruments, SMAP biosensors bring a whole new level of sensitivity to biolayer interferometry (BLI) technology. Gator Bio is committed to innovation and improving upon ordinary BLI to help users.

Gator^TM Small Molecule, Antibody, and Protein (SMAP) Biosensors are useful for the study and determination of small molecule binding kinetics. The proprietary surface chemistry allows for high capacity immobilization of biotinylated proteins (recommended molar coupling ratio of less than three) or proteins expressed with an AviTag^TM for a wide range of molecular weights. Following immobilization, the ability of the biotinylated protein of interest to bind to small molecules can be measured to determine the kon, koff, and KD of interaction.

BENEFITS of SMAP

• Higher sensitivity

• More signal

• Compatible with small molecules and biomolecules of a wide range of sizes

Gator Bio

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