account_circle Sign In monetization_on Sell Equipment

Unlock Greener, Smaller, Compliant HPLC with Capillary Scale LC

Download the Application Note: Adapting Pharmaceutical Monographs Using USP 621 Guidelines

Are you looking to reduce solvent use, operating costs, and lab footprint—while still meeting USP method compliance?

This application note, authored by Sam Foster and Milton Lee, demonstrates how to successfully adapt a United States Pharmacopeia (USP) monograph for hydrochlorothiazide to capillary scale HPLC using the USP <621> guidelines. The study compares chromatographic performance across capillary and analytical scale systems using the Axcend Focus LC—a compact LC platform optimized for ultra-low flow separations.

What You’ll Learn:

• How to modify flow rate, gradient, injection volume, and column specs per USP <621>
• Quantitative comparison of capillary and analytical scale performance
• How capillary LC achieved 99.6% reduction in solvent waste
• Validation that the Axcend Focus LC meets USP monograph system suitability criteria

Who Should Read This:

• Pharmaceutical scientists working in QC or method validation
• Regulatory compliance professionals
• Labs seeking more sustainable, small-footprint HPLC solutions

Get the Application Note Now See how capillary scale HPLC using the Axcend Focus LC can support USP- compliant pharmaceutical analysis while saving space and resources.

DOWNLOAD THIS APPLICATION NOTE

Become a member and enjoy exclusive benefits

Create an account now for exclusive benefits, personalized recommendations, and seamless order tracking. Elevate your lab experience today!