Ensuring Raw Material Integrity in Synthetic Peptide Manufacturing

The global demand for peptide-based therapeutics—especially GLP-1 receptor agonists (GLP-1 RAs) used for diabetes and weight management—has surged, driving the need for more efficient large-scale synthetic peptide manufacturing. To keep pace, producers must ensure the integrity and identity of every raw material involved in the process.

In this whitepaper, researchers demonstrate how the Agilent Vaya Raman System enables rapid, noninvasive verification of Fmoc-protected amino acids, the critical building blocks for synthetic peptide production

What You’ll Learn

• The challenge – How growing peptide demand is straining current production capacity and increasing the importance of raw material verification
• The innovation – How the Agilent Vaya Raman System uses spatially offset Raman spectroscopy (SORS) for identity verification through containers, eliminating the need to open sensitive materials
• The impact – How this approach preserves material integrity, prevents contamination, and reduces production bottlenecks
• The results – Rapid, accurate differentiation of Fmoc-protected amino acids in less than 40 seconds, with clear Pass/Fail outcomes

Download the Whitepaper

See how the Agilent Vaya Raman System is redefining raw material verification in peptide manufacturing—helping pharmaceutical producers meet growing demand with speed, safety, and confidence.