Purify large quantities of raw materials

Do you need to purify several hundred grams of the compounds of interest in a single run? If you want to do this with complete confidence and unparalleled results, then a puriFlash® device is all you need.
With its 750 ml/min and its column support with which Flash columns can be adapted up to format F1600, you will receive a maximum amount of products and your purification yield will always be optimal.

Its long-lasting reliability and robustness, as well as its safety features are key benefits to carrying out your productions semi-continously and with volumes of up to several hundred grams of the compounds of interest.
With the puriFlash® 5.007, you benefit from production continuity on the same device, regardless of the scale-up factor.

Components

Control unit
Pump
UV detector
Fraction collector
Solvent tray with drainage system
Integrated column holder
Integrated Dry-Load holder

Pump

Flow rate range: 10 mL/min to 825 mL/min
Max. operational flow rate: 825 mL/min
Optimum flow rate for columns up to F3000 format
Flow rate accuracy: +/- 2 % over 100 to 750 mL/min & 5 to 12 bar
Flow rate repeatability: < 0.25
Flow rate linearity: 0.98 < linearity < 1
Pressure range: 0 to 15 bar
Max. operational pressure: 15 bar
Quaternary gradient valve
Gradient tolerance step: < 3.5 %
Washing disks

Injection

Injection mode: liquid or solid
RFID technology: automatic detection of the Dry-Load

Detection

UV detector 200-400 nm
UV detector 200-800 nm
”DAD” technology
Multi-wavelength and scan collection over a band of 200 nm
Spectral visualization and confirmation of purity
Flow cell pathway: 0.3 mm / 80 µL

Column & support compatibility

Normal phase(NP)
Particle sizes: 15 µm, 25 μm, 30 μm, 40 μm , 50 μm
Reverse phase (RP)
Particle sizes: 30 µm, 50 µm
Format: all Flash columns up to F1600 format & Dry-Load up to F0330 format are compatible
Integrated column holder
Integrated Dry-Load holder
RFID technology: automatic detection of the columns

Fraction collector

Capacity:
● 3 racks
● 42 test tubes (29,5 x 200 mm)
Technology:
● Automatic cleaning of the fraction collector needle (to avoid cross-contamination with the previous purification)
● RFID: automatic detection of the racks installed in the fraction collector

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