The Importance of Microplate Readers in 3D Biology: Whitepaper

The arrival of 3D biology represents a paradigm shift in disease modeling and drug development. Traditional in vitro 2D plate-based cell models are being replaced by 3D cell model organoid systems which better represent in vivo physiological traits and biological processes of native tissue.

Organoids provide cell and tissue-type insight that aims to accelerate the pace of disease research and drug screening. Microplate readers serve critical roles in 3D biology workflows, such as organoid viability and the effects of compound screening among other essential applications.

This whitepaper explores a recent study titled “A walkaway solution for assessing drug effects in patient-derived colorectal cancer organoids” describing the use of the SpectraMax® iD5 Multi-Mode microplate reader in cancer organoid cell viability assays.