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The Latest Immunoassay Kits and Instruments for Vitamin D Testing
Technical Insight
With the emerging importance of Vitamin D in cardiovascular disease, cancer, diabetes, and other pathologies, the latest immunoassay technologies are proving essential in ensuring accuracy, precision, and throughput for today’s testing needs.
Shedding Light on Advances in Vitamin D Testing
Technical Insight
In consideration of national Vitamin D Day - which took place on November 2nd - it’s a perfect time to shine light on the evolution of methods to track accuracy and clinical utility of this essential compound.
Advancements in Mass Spec Analysis of Food Components, Additives, and Contaminants
Technical Insight
Mass spec imaging (MSI) is growing in the food testing field, with new techniques aiming to analyze spatial distribution to improve quality, food safety, nutritional content, and the identification of key food factors.
Handheld Raman Analyzers for Rapid In-Field Chemical Analysis
Technical Insight
This guide from Rigaku explores the many applications of handheld Raman analyzers in the field.
The Evolution of NGS Technologies: Closing in on Personalized Genome Sequencing
Technical Insight
New next generation sequencing technologies are lighting the way towards the holy grail of personalized genome sequencing
The Hemp Harvest in Croptober
Technical Insight
Hemp Harvest or Croptober - regardless of what we choose to call the season, it’s a time to sit back, relax, and report a few hemp-centric updates from the field.
The Latest HPLC Columns for Vitamins, Natural Products, and Small Molecule Separations
Technical Insight
Products with increased retention and selectivity qualities designed to address challenging separations.
New Microplate Technologies for Complex Cell Analysis and Screening Workflows
Technical Insight
From automated flow cytometry to complex cell imaging and screening, the latest microplate-based technologies are evolving to enable a multitude of applications and fields.
Updates on Cannabis Research and Regulation
Technical Insight
Microbial Testing Updates and New Initiatives for Cannabis Research
Automated Liquid Handling: Resources to Match Products with Solutions for Your Lab
Technical Insight
Exploring the latest lab automation offerings suited for the needs of your lab
Advancements in Mass Spec Imaging Presented at ASMS
Technical Insight
Low micron-scale resolution and protein compound co-localization were two MALDI Imaging innovations showcased at the ASMS conference this year
Electron Diffraction of Nanocrystals — Going beyond the Limits of X-Ray Diffraction with the Rigaku XtaLAB Synergy-ED
Technical Insight
Recognizing the potential of electron diffraction for the crystallography community, Rigaku and JEOL embarked on a partnership to develop the world’s first commercially available electron diffraction system. This collaboration culminated in the XtaLAB Synergy-ED, a dedicated electron diffractometer.
Tips for Buying a Used Centrifuge
Technical Insight
Buying pre-owned lab equipment can be a great way to stretch your budget. However, navigating the used equipment market can be challenging. If you’re looking to buy a secondhand centrifuge, here are six tips to ensure you get a good product.
Tips for Troubleshooting Your Centrifugal Evaporator
Technical Insight
Here are three problems that you may experience with your centrifugal evaporator, as well as troubleshooting steps for each.
Research and a Better Understanding of the Medicinal Properties of Cannabis Terpenes
Technical Insight
Despite the wide-ranging significance of terpenes, isolation and pharmacological use of these compounds has been limited until this point. Recent research advancements, however, may change the course of such work – making terpenes ripe for pharmaceutical development and other important applications.
The Scientific Connections Between Hemp, Honey, and Bees
Technical Insight
Recent studies show that the steady introduction of industrial hemp may be creating an agroecosystem that supports the health and well-being of bees and other pollinators.
New GC Products to Address Efficiency and Productivity
Technical Insight
From swapping columns to identifying leaks, new GC product offerings focus on efficiency and productivity to boost performance
Innovative New Technologies for Antibody and Serology Testing
Technical Insight
The Covid challenge has brought to light many new, cutting-edge approaches towards antibody testing
Mass Spec in the Clinical Lab: Product Updates
Technical Insight
The presence of mass spec continues to grow in the clinical testing space, and new FDA-approved In vitro diagnostics are helping lead the way.
Product Updates in FTIR Microscopy and Mass Photometry for Particle Imaging and Analysis
Technical Insight
A flurry of new products has launched to meet the needs for single particle imaging in materials science and biomedical applications
Evolving PCR Technologies for Covid-19 Testing and Future Clinical Applications
Technical Insight
The critical role of RT-PCR during the SARS-CoV-2 pandemic demonstrates that PCR technology not only continues to evolve, but is growing to meet challenges of unprecedented scale and importance.
Poisoned by Plastic: A Closer Look at HPLC Analysis of BPA and Plasticizers in Water Bottles
Technical Insight
Adam Moore, HPLC Applications Chemist at Hamilton Company, discusses the use of HPLC and polymer column separations in exploring the presence of plasticizers leaching from consumer plastic bottles.
2022 Mass Spec Trends and New Product Outlook
Technical Insight
New product trends in the areas of ion mobility, novel separation technologies, and single-cell proteomics
Mass Spectrometry 2021 New Technology Roundup
Technical Insight
We take a moment to review several innovative technologies released this year, designed to address current trends and challenges in biopharma and proteomics.
The Latest Products for COVID-19 Research, Testing, and Therapeutic Development
Technical Insight
COVID-19 related products have and will continue to be at the forefront of life sciences research and therapeutic development. Here are some new product updates.
Microscopy and Imaging Developments in the Life Sciences Universe
Technical Insight
Our understanding of the life sciences is expanding, thanks to recent developments in state-of-the-art microscopy and imaging technologies
Allergen Testing of Food Products: On-site, In the Lab, and At Home
Technical Insight
Accurate and reliable testing for the presence of allergens in food products is of the utmost importance, for both compliance with regulations & the safety of consumers.
Advanced Chemical Fingerprinting of Food and Beverages using LC-MS
Technical Insight
Two recent research studies using LC-MS — focused on the analysis of beer and e-cigarettes — demonstrate the power of the technology for applications of importance and emerging concern.
The Potential for Next Generation Sequencing in Diagnostics, Infectious Disease, and Precision Medicine
Technical Insight
Long awaited applications may be well within reach for new NGS technologies
The Hamilton HPLC Applications Library: A Resource for Cannabis Testing Solutions
Technical Insight
We recently spoke with Adam Moore PhD, HPLC Applications Chemist at Hamilton Company, to learn more about the exciting applications of the company’s HPLC technologies in the rapidly growing cannabis and hemp testing industries.
Ongoing Research and Product Innovation as the COVID Battle Rages On
Technical Insight
As SARS-CoV-2 virus shifts strategies, new products and technologies step up to the challenge
Hemp Vs Marijuana: Key Differences to Keep in Mind for Your Hemp Lab
Technical Insight
Whether working with hemp for fibre, grain, or CBD production, the processes involved are very different than with marijuana. CBD extraction is also a different process from THC extraction. Here we explore the differences in the plants, their processing,
Analysis of Hand Sanitizer Products using Handheld 1064 nm Raman
Technical Insight
The use of hand sanitizers is becoming part of the everyday norm, and demand around the world has grown exponentially over the recent months. There is a global focus on hand sanitizer manufacturing, quality control, and confirmation and the handheld Raman
The Impact of Microplate Imaging Solutions on Covid-19 Research and Therapeutic Development
Technical Insight
From consumables and pipettes to diagnostic testing kits and much more, the life science industry has continued to innovate during these challenging times. A keen area of focus for new Covid-19 research solutions includes microplate and imaging technologi
Key Considerations for Microbial Contaminants Testing in Cannabis
Technical Insight
Molecular methods such as quantitative polymer chain reaction (qPCR) have gained significant momentum for use in microbial testing of cannabis. Here are a few key considerations for use of these methods and commercial kits.
Polymorph Monitoring with the Rigaku Progeny 1064 nm Handheld Raman Analyzer
Technical Insight
The Rigaku Progeny 1064 nm handheld Raman analyzer is a versatile tool and a powerful solution for pharmaceutical polymorphs analysis and other challenging applications.
Lab Automation and Connected Lab Solutions
Technical Insight
Lab Automation has become a concept that transcends individual pieces of equipment -- with new solutions meant to connect devices through a central platform designed for scheduling, controlling, and managing data.
Sample Preparation of Plant and Animal Tissue in Remote Locations: Tools and Methods
Technical Insight
Molecular biology methods are increasingly being used to monitor agricultural products directly, at the site where the crops and animals are commercially produced. Innovations in Tissue Extraction and Tissue Processing help to ensure the best possible ou
Key Breakthroughs in Single-Cell and Single-Molecule Microscopy
Technical Insight
Two recent breakthroughs push the limits of resolution even further than before, enabling our ability to view single-molecule interactions and single cell activities in live cells with unprecedented detail.
Updates on the Frontier of Pharmaceutical and Medicinal Cannabis
Technical Insight
As the landscape changes and further sources of cannabis become available for research, the medicinal cannabis and pharmaceutical fields stand to benefit in a multitude of ways. Here are a few recent developments.
Genetic Variant Tracking and New Sequencing Solutions
Technical Insight
The past year has accelerated the development of certain trends and new technologies – notably advanced genetic sequencing products and solutions.
Progress in the Science of Cannabis Consumables
Technical Insight
Concerns over stability and bioavailability continue to challenge the consumables landscape, although research efforts are yielding interesting and important insights
Cannabis vs Coffee: The Science Behind the Ultimate Extraction
Technical Insight
Regardless of the particular coffee roast or cannabis strain, there is a science to extraction that underlies the true essence of these plants and their extracted products.
Liquid Chromatography and LC-MS Products to Start the New Year
Technical Insight
2021 looks to be a year of significant growth and innovation in the HPLC and LC-MS fields. Here are a few early developments in the new year.
Advancements in SARS-CoV-2 Testing and Research Technologies
Technical Insight
Here are a few notable developments that will continue to advance our understanding of COVID-19 throughout 2021 and beyond.
Cannabis Laboratory Product Trends in the New Year
Technical Insight
We take a moment and examine a few new product trends that will help the industry gain stronger footholds in the new year and beyond.
Mass Spec Trends to Watch
Technical Insight
Several trends in particular will continue to change the mass spec landscape in 2021 and beyond.
Cold Chain Storage Solutions for the Lab, the Clinic, and the Road: Interactive Infographic Timeline
Technical Insight
The Cold Chain: Storage Solutions for the Lab, the Clinic, and the Road interactive infographic is a living resource -- this post serves as a chronology of the infographic, tracking developments and citing sources in this vitally important product area.
Mass Spec-Based FDA-Approved COVID-19 Testing Platforms
Technical Insight
Several new FDA-approved tests based upon mass spectrometry showcase the power of mass spec, not only as a discovery technology, but as a capable platform for unprecedented public health challenges.
At-Home COVID-19 Testing Kits: How Do They Work?
Technical Insight
The growing number of at-home sample collection devices and testing products drives the question -- how these covid-19 testing solutions work?
Covid-19 and the Brain: Innovative Cell Culture Tools to Advance Research
Technical Insight
Researchers have begun to dissect SARS-CoV-2 effects on the blood brain barrier, making use of innovative cell culture models, techniques, and equipment
A Glance at Next Generation Sequencing Technologies for COVID-19 Applications
Technical Insight
The successful application of NGS technologies to a problem of this scale and scope speaks to the power of innovation. Here are a few new NGS solutions for COVID-19 research applications.
Mass Spectrometry Wields its Might in the Battle Against COVID-19
Technical Insight
Mass spectrometry once again wields its might, combating the COVID-19 pandemic from multiple aspects. Here is a brief look at some of the method development and collaborative efforts that are leading the charge.
Antibody, Immunoassay, and Microplate Technologies for COVID-19 Testing Applications
Technical Insight
The advent of new microplate technologies and advanced testing solutions will continue to fortify the fight against COVID-19, from the research lab to the clinic.
3 Important Considerations in Cannabis Contaminants Testing
Technical Insight
We discuss three “C”s of contaminants testing – complexity, compliance, and costs, and the importance these bear on the success of operations.
New Product Trends for COVID-19 and Infectious Disease Research
Technical Insight
New products and technologies are helping to arm scientists and medical professionals – providing the insight needed in the fight against this unprecedented viral disease.
Hot Spots in the World of Medicinal Cannabis Development
Technical Insight
Solubility, stability, dose release, and bioavailability — progress in these areas is essential for the effectiveness of cannabis formulations, and the future of cannabis drug development.
Ultra-High Resolution Imaging: The New Benchmark in Molecular Microscopy
Technical Insight
The world of microscopy has a rich and vivid history -- two recent breakthroughs shine even greater light on an already brilliant field of view.
Emerging Product Solutions for a New Cannabis Landscape
Technical Insight
The post COVID-19 landscape will incorporate new tools designed to address challenges in both the lab and the field -- technologies that may be essential as we move to higher standards of safety, efficiency, and automation.
New LC-MS and Glycan Analysis Products for SARS-CoV-2 Research and Other Challenging Applications
Technical Insight
Research into SARS-CoV-2 spike protein and other areas are contributing to the development of viable vaccines, drugs, and therapeutic antibodies -- all benefiting from new glycan analysis and LC-MS solutions.
Real-Time RT-PCR Test for the Detection of SARS-CoV-2: How Does it Work?
Technical Insight
Understanding the strengths and limitations of real-time RT-PCR is essential for examining the current virus outbreak and for those that may emerge in the future.
Cannabis Consumables and Critical Advancements in Testing Standardization
Technical Insight
Analytical methods standards organizations such as AOAC International are making significant headway in providing scientists and laboratories with consensus-driven, verified processes for universal food safety testing.
Supercritical Fluid Chromatography (SFC): New Products and Emerging Applications
Technical Insight
New and emerging supercritical fluid chromatography applications have brought with them a host of new technologies -- with elevated performance, efficiency, and green chemistry as key drivers.
What is an Antibody Serology Test - How Does it Work - and Why is it Important?
Technical Insight
<p>Detecting invasion by the SARS-COV-2 virus (the causative agent of COVID-19) is the crucial first step in identifying pathogen exposure. Measuring the human immune response is the vital next stage to quantify true infection rates and to decipher the de
Emerging Trends in Infectious Disease: Interactive Infographic Timeline
Technical Insight
The Emerging Trends in Infectious Disease Interactive Infographic is a living resource -- this post serves as a chronology of the infographic, citing ongoing developments in the areas of: Detection and Containment, Diagnosis and Treatment, Laboratory Equi
The Virus Surface to a Novel COVID-19 Vaccine Candidate: The Journey of the SARS-CoV-2 Spike Protein
Technical Insight
Intensive analysis of the spike protein led to the development of the first vaccine candidate approved for clinical trials. Perhaps overshadowed, is the unprecedented collaboration between academic scientists, government institutions, and private industry
Structural Imaging Approaches Shed Important Light on Novel Coronavirus Entry and Infectivity
Technical Insight
High-resolution cryo-electron microscopy imaging of the CoV spike protein complex has revealed both expected and novel structural elements – signifying capabilities previously not observed in this family of coronaviruses..
The Challenges Behind Approved COVID-19 Virus Testing and Availability
Technical Insight
Challenges with the approval of COVID-19 test diagnostics uncovered serious process issues that are now being resolved in order to contain the current outbreak and to fight future pathogens.
Digital PCR: Details and Emerging Applications of this Incredibly Powerful Molecular Tool
Technical Insight
Digital PCR or dPCR extends from traditional qPCR, namely in the accuracy and precision of absolute quantitation and the manner in which target DNA is measured. Here we explore details behind the application of this powerful technology.
Mass Spectrometry for Clinical Applications: Challenges and Solutions in the New Decade
Technical Insight
The new decade holds both promise and remaining challenges for widespread adoption of mass spectrometry in the clinical lab
The Beadbeater and the Evolution of Mechanical Cell Disruption Technologies
Technical Insight
Beadbeating technology was developed and originally commercialized by BioSpec Products in the late 1970’s -- over time becoming the preferred method for laboratory cell disruption applications. Continued innovation has focused on the needs of labs to ac
The Most Impactful Cannabis Industry Developments of the Year
Technical Insight
Hemp legalization, safety concerns, challenges and solutions in testing -- major developments in 2019 spotlight progress in the industry and areas for growth and maturation for 2020 and beyond
The Era of Next-Generation Mass Spectrometry Imaging
Technical Insight
Non-targeted, unlabeled, high-resolution spatial mapping – benchmarks of the new era of next-generation mass spectrometry imaging technologies.
The Benefits of Direct Mercury Analysis: A Technology Review
Technical Insight
With over 2500 systems installed worldwide, direct mercury analysis has proved itself to be a viable complementary technique to CVAA and ICP-MS for carrying out mercury determinations.
Terpenes Testing and Challenges of Standardization in the Cannabis Industry
Technical Insight
Terpenes testing presents difficulties across the industry, largely due to the nature of the compounds and the diversity of instrumentation and methods employed by testing laboratories. This issue highlights the need for better defined standardized method.
Single Channel Versus Multi-Channel Electrophysiology: How Does it Work?
Technical Insight
Multi-channel electrophysiological recordings are the sum total measurements of electrical activity across a cell membrane. Single-channel recordings are the discrete measurements of individual channel activity. We summarize the details of the techniques
Mass Spectrometry Pesticides Detection in Modern Food Safety and Testing
Technical Insight
Modern food safety and testing employs state-of-the-art mass spec methods and technologies for applications in import screening, domestic profiling, and many other important areas of food science.
Selecting Microwave Digestion Technology for Measuring Heavy Metals in Cannabis Products
Technical Insight
This article describes the basic principles of the major types of microwave digestion technology and offers suggestions as to which might be the best approach for cannabis heavy metals testing based on sample matrix, digestion efficiency, sample throughpu
Cannabis Pesticides Testing and Quantification Using Reference Standards: How Does it Work?
Technical Insight
Access to high-quality analytical materials and resources can ensure testing laboratories operate at the highest levels of accuracy and precision — supporting transparent, clean, and safe cannabis products.
Adding Depth to Your Research: A Look at 3D Cell Culture
Technical Insight
In recent years, huge steps have been made to standardize and manufacture equipment for 3D cell culture—making it cheaper, simpler and more reproducible.
Analytical Cannabis Testing and the Importance of High-Quality Water
Technical Insight
High-performance water filtration systems, such as the arium® Series water purification system from Sartorius, provide long-term practical and economical advantages to cannabis testing laboratories and address the needs of this changing industry.
Cannabis Heavy Metals Contaminant Testing by ICP-MS: How Does it Work?
Technical Insight
Inductively coupled plasma mass spectrometry (ICP-MS) methods have become the state-of-the-art in cannabis testing, producing the highest sensitivity and specificity for metal contaminants analysis – but how do these techniques work?
Three Current Trends in Automated Liquid Handling for Clinical Applications
Technical Insight
A look at liquid handling trends and emerging solutions for clinical challenges -- Multiplexing, Microfluidics, and Sustainability.
The Bio-Rad Droplet Digital PCR Publications Database
Technical Insight
With more than 6000 published studies and growing, nowhere is the power of Droplet Digital PCR technology further apparent than Bio-Rad’s expansive ddPCR Publications Database.
Therapeutic Potential and the Medicinal Cannabis Journey
Technical Insight
A novel antibiotic, a treatment for intractable illness, a cure all for chronic pain -- a few of the myriad potential applications for this wondrous plant.
ASMS Review 2019: Big Fish Emerge in the Sea of Mass Spectrometry
Technical Insight
The 2019 American Society for Mass Spectrometry annual conference was held in Atlanta Georgia Jun 3-7. Here are a few of the many impressive technologies that surfaced.
Opportunities in the Evolving World of Cannabis-Based Pharmaceuticals
Technical Insight
The science behind the evolving world of cannabis-based pharmaceuticals will ultimately pave the way towards better, more effective treatments for a wide range of human conditions and disease.
The Combined Power of LC-MS and Artificial Intelligence
Technical Insight
The power of AI is being integrated into liquid chromatography and other technology platforms, with the ultimate goals of alleviating bottlenecks and resource consumption while boosting efficiency and productivity.
The Cannabis Workflow and the Importance of Temperature Control
Technical Insight
Creating the right systems to maximize the quality of temperature control plays a vital role in creating the most productive cannabis extraction workflow.
CBD Potency Testing of Hemp-Derived Products
Technical Insight
As part of a series looking at safety and quality testing of cannabis products, this article focuses on analysis of hemp and methods for CBD/THC potency determination.
Cannabis Terpene Profiling using the GCxGC-TOFMS Pegasus BT 4D System from LECO
Technical Insight
Compound profiling by multi-dimensional gas chromatography combined with high performance mass spectrometry offers a powerful approach for cannabis strain type authentication, quality control, and study of the underpinning details of the “entourage effe
Ion Mobility Mass Spectrometry: Another Separations Layer for Complex Applications
Technical Insight
Ion Mobility Mass Spectrometry offers a unique layer of separations power and adds yet another dimension for complex, high-throughput applications.
Forging the Path of the Imaging Resolution Revolution
Technical Insight
As imaging technologies continue to forge ahead, a few areas in particular promise to make for an interesting year and offer extraordinary vision for what is to come.
New Technologies Enhance the Speed and Accuracy of Flow Cytometry Workflows
Technical Insight
Multiplexed detection, automated workflows, and advanced focusing technologies – enabling breakthrough applications in the fields of immunology, oncology, cell therapy, and beyond.
3 Mass Spectrometry Trends to Drive Omics Data Enhancement through Hybrid Technologies
Technical Insight
These trends may enable more complete biomarker panel validation, greater coverage in complex metabolomics areas such as lipidomics, and ultra high-resolution imaging of complex tissues such as brain.
PRP-C18 Polymer Columns: A Next Generation Solution for Synthetic Oligonucleotide Purification
Technical Insight
The PRP-C18 polymeric columns from Hamilton are a state-of-the-art solution for oligonucleotide purification, providing the performance, durability, and flexibility for the most demanding next generation applications.
The Effects of Cannabis on Brain Development: Research Outlook
Technical Insight
The 2018 Society for Neuroscience conference showcased important results based upon research on the effects of cannabis on brain development. With cannabis legalization preceding at an ever-increasing clip, it is more imperative than ever to explore the i
Magnetic Resonance Imaging of the Brain: Unprecedented Power and Resolution
Technical Insight
The latest MRI systems have now surpassed the 10 Tesla mark -- making clear the power of the technology for cutting-edge brain research and advanced diagnostics.
Mass Spectrometry Investigations of Food and Beverage Quality and Safety: Time for some Wine
Technical Insight
Here we take a look at modern mass spectrometry approaches for food and beverage analysis – focusing this month on wine.
Cannabis Research Enters a New Phase of Growth: Research Outlook
Technical Insight
Cannabis research is approaching a differentiation and maturation phase – where public and private efforts are yielding substantial growth for the medicinal cannabis field.
Multi-platform Next Generation Sequencing for Cancer Diagnostics: Research Outlook
Technical Insight
Harnessing the power of next generation sequencing technologies, in combined approaches, can improve the speed, accuracy, and quality of diagnostic results.
3 Current Trends in the Food and Beverage Industry
Technical Insight
The food and beverage industry will benefit significantly by staying ahead of continuing trends. While safety remains a top priority, technology and consumer habits will undoubtedly be drivers in efficiency and long-term sustainability.
Syringe Infusion Pumps in Brain Microdialysis Procedures and In Vivo Testing
Technical Insight
The performance of the syringe infusion pump is vitally important, impacting not only analysis of an experimental system but the potential effects of CNS drugs, neurotransmitter modulators, and other compounds in vivo.
Laboratory Centrifuges: Advanced Features for Modern Applications
Technical Insight
Advanced features, precision control, and operator resources aim to extend centrifuge instrument capabilities and performance.
ASMS 2018: The Evolution of the Industry and the Reality of Next Generation Proteomics
Technical Insight
The evolving state of the industry and the reality of next generation proteomics - two themes evident at ASMS 2018 that may well change the MS world.
Spectroscopic Analysis of Microplastics in the Environment
Technical Insight
Spectroscopic technologies are proving increasing vital to analysis of plastics contamination in the environment
Fourier Transform Infrared (FTIR) versus Raman Spectroscopy
Technical Insight
Although FTIR and Raman spectroscopy are complementary, the techniques are based on distinct physical processes and measurements capabilities.
Genetic Sequencing and Polymerase Chain Reaction Technologies: Products and Emerging Trends
Technical Insight
Sequencing methods have evolved to encompass high-throughput, high-resolution methods based on advanced capillary and microfluidic technologies.
Pros and Cons of Continuous Flow versus Batch Processing Systems
Technical Insight
Continuous flow systems can overcome traditional reactor limitations, while batch systems can offer process versatility without breaking containment.
Liquid Chromatography: Technology Trends and Fundamentals
Technical Insight
We detail some of the fundamentals of liquid chromatography and examine emerging trends and new products -- with special focus on nanoflow and chip-based technologies.
Lab Water and the Impact on Liquid Chromatography Performance
Technical Insight
Poor quality data such as shifting retention times, loss of resolution, or ghost peaks could be an indication of contamination caused by lab water quality.
Hemp versus Hops: Past, Present, and Future for an Unlikely Pairing
Technical Insight
A closer look at the similarities and differences — as well as the chemicals and compounds — that weave these two plants together in natural synergy.
Advances in Clinical Mass Spectrometry: Proteomics and Phenomics
Technical Insight
Beyond instrument horsepower, enabling solutions are needed more than ever to ensure quality and efficiency of upstream workflows. Here are recent examples.
Automated Cell Counters: Advanced Products and Technologies
Technical Insight
Modern technologies strive to remove variability in staining, sample transfer, and the influence of the user. Here we detail a few advanced systems.
High-Performance Syringe Pumps and Evolving Microdispensing and Manufacturing Applications
Technical Insight
Modern microdispensing processes require low volumes of reagents, delivered with high accuracy and precision often under high temperature and pressure.
Advances in Cannabis Extraction Methods and Equipment
Technical Insight
Advances in efficiency, precision, reliability, and scalability are critical to meet increasingly stringent guidelines and overall growth of the industry.
Downstream Processing and Refinement of Cannabis Concentrates
Technical Insight
The various methods of cannabis extraction can produce a diverse range of cannabis concentrates. Here we briefly discuss downstream fractionation methods.
The Best Cannabis Extraction Methods for Marijuana Concentrates
Technical Insight
We detail various extraction techniques for the production of cannabis concentrates, offering insight regarding benefits and associated costs.
Flow Cytometry: Principles, Applications, and New Instrument Technologies
Technical Insight
Flow Cytometry is a quintessential method for cell characterization. Here we briefly review principles, applications, and a few new instrument platforms.
Fast and Easy Cannabis Potency Testing Using an Entry Level Agilent 1260 Infinity LC
Technical Insight
This Application Note details a fast and simple analytical approach for quantitation of 9 Cannabinoids of interest using an Agilent 1260 Infinity.
Advances in Cannabis Processing Equipment
Technical Insight
Further understanding of cannabinoid production will lead to even cleaner and more efficient processing of compounds for medicinal purposes and beyond.
Chemical Process Development: The Role of Precision Syringe Pumps in Continuous Flow Systems
Technical Insight
The continuous flow reactor development phase requires high performance syringe pumps to deliver precision volume, pressure, and temperature control.
Emerging Trends in Compact Mass Spectrometry
Technical Insight
These technologies offer a glimpse of future directions in analytical chemistry, molecular medicine, and applications such as point-of-care diagnostics.
Emerging Mass Spectrometry Technologies for Clinical Applications
Technical Insight
Several important developments in 2017 offer promise for significant advancement in the area of clinical mass spectrometry.
Emerging Mass Spectrometry Imaging Technologies
Technical Insight
The pace of mass spec imaging technology innovation indicates a greater number of products and solutions will reach mainstream use in 2018 and beyond.
2018 Mass Spectrometry Emerging Technology Outlook
Technical Insight
With the new year comes the promise of greater MS performance, more powerful analysis solutions, and a broader scope of interrogation than previously seen.
Precision Syringe Pump Applications in Biopharmaceutical Drug Development
Technical Insight
Programmable precision syringe pumps operate in many stages of biopharmaceutical preclinical development -- from protein analysis to bioprocess applications.
Hemp versus Marijuana: CBD vs THC
Technical Insight
Considering the important distinctions between CBD and THC and their origin, it is only fitting to detail the difference between these cannabis types.
Cannabidiol versus Tetrahydrocannabinol: CBD vs THC
Technical Insight
With hemp now legal in the US, it is worth reviewing the differences between CBD and THC -- which range far beyond chemical and pharmacological.
2018 Cannabis Processing and Testing Outlook
Technical Insight
We offer an overview of the medicinal cannabis industry with a focus on emerging processing and testing technologies that will make 2018 a banner year.
Polymerase Chain Reaction (PCR): Tips and Technologies
Technical Insight
We review popular technologies and the equipment involved, briefly discussing important aspects to keep in mind when optimizing the technique.
Mass Spectrometry Technology and Product Development Snapshots
Technical Insight
A new technology aims to simplify the challenge of MS ionization, while a new product streamlines the workflow from sample to protein characterization.
The Compact Mass Spec Field Continues to Expand
Technical Insight
2017 saw the advent of several new compact mass spectrometry platforms and applications, demonstrating the continued versatility and power of this concept.
MALDI Imaging Reaches a Milestone
Technical Insight
MALDI technology has reached the 30th anniversary milestone, and 2017 brought several new products to the areas of MALDI imaging and data solutions.
A Coming of Age for Clinical LC-MS Mass Spectrometry
Technical Insight
2017 has seen the launch of several breakthrough clinical LC-MS technologies, driving new areas of clinical exploration and anticipation for what's to come.
2017: A Decorated Year for Mass Spectrometry
Technical Insight
As 2017 draws to a close, we review notable innovations and scientific accomplishments from the year, and make a few predictions for the year to come...
Evolving Extraction Methods for the Growing Cannabis Industry
Technical Insight
The type of product dictates not only the plant strain and enrichment for specific components, but the extraction method to isolate those compounds.
Progress in Cannabinoid Purification and Testing
Technical Insight
Great strides have been made with technologies to suit cannabis grinding and milling, compound extraction, and cannabinoid purification and testing.
Cannabis Science Hits Its Stride
Technical Insight
2017 witnessed an array of achievements in research, pharmaceuticals, education, and policy – evidence of significant progress and a case for true optimism.
Progress in 3-D Imaging Microscopy and Brain Mapping
Technical Insight
High-resolution mapping of neurons and neuronal connectivity in the brain has required innovative multi-beam electron microscopy approaches.
Syringe Pumps and Perfusion Systems for Neuroscience Research Applications
Technical Insight
Syringe Pumps and Perfusion Systems for Neuroscience Research.
The Implications of Cannabidiol and the Brain
Technical Insight
The broad potential therapeutic profile and ongoing clinical trials indicate that many of the true medicinal qualities of CBD will soon come to light.
Emerging Support for Cannabis as an Effective Alternative to Opioids in Pain Treatment
Technical Insight
A growing number of studies have reported that cannabis use can diminish the negative and addictive effects of opioid use without sacrificing pain relief.
Recent Results Indicate that Cannabis Reverses Aging Processes in the Brain
Technical Insight
The study has interesting and exciting implications for the potential of cannabis-based neurodegenerative disease applications.
Versatile and Efficient Benchtop Scanning Electron Microscopes
Technical Insight
Benchtop scanning electron microscopes address size efficiency without sacrificing features that make the technology powerful for many research applications.
Key Stages in Biomarker Identification and Validation
Technical Insight
The road to biomarker validation is long and arduous, however modern solutions are paving the way for a greater range of entities with untold potential.
Therapeutic Discovery: Old Challenges and New MALDI-TOF Solutions
Technical Insight
The area of high-performance MALDI-TOF MS has undergone leaps in technology making MALDI better able to produce actionable information from complex samples.
New Technologies in Metabolomics Research
Technical Insight
The latest innovations maximize accuracy, resolution, and throughput without sacrificing depth, to handle complex and demanding metabolomics applications.
Synthetic Cannabinoids: The Alternative Route
Technical Insight
Synthetic cannabinoid treatments may include those that target multiple indications through specialty formulations and combination therapies.
Routes of Administration and Bioavailability for Cannabis Therapeutic Dosing
Technical Insight
The bioavailability and effective routes of administration are critically important parameters in cannabis-based therapeutics.
Biosynthesis and Medicinal Value of Key Cannabinoids
Technical Insight
Stratifying the therapeutic value of cannabis compounds will continue to rely upon improvements in cannabis processing and testing methods and equipment.
The Promise of Plant-based Cannabinoid Therapeutics
Technical Insight
Further evidence to support plant-based cannabis therapeutics as both effective and safe may have positive effects on the medical marijuana field as a whole.
LabX Industry Insights: Lab-on-a-Chip Applications for High-quality Precision Syringe Pumps
Technical Insight
Modern systems require precision fluid flow, fluid exchange, and custom functionalities – demanding features only high-quality syringe pumps can deliver.
LabX Industry Insights: Microfluidics and the Essential Role of High Performance Syringe Pumps
Technical Insight
High quality syringe pump instruments must deliver accurate fluid volumes, precision flow rates, and optimal functionality in microfluidic applications.
Microplate Nephelometer Technology for Light-scattering and Turbidity Measurements
Technical Insight
The technique has applications in drug solubility screening, protein binding activities, microbial growth analysis, petroleum process control, and others.
Microplate Technologies for the Modern Laboratory
Technical Insight
Technology innovation has been both the driver for decreased sample size as well as increased experimental complexity and scale in microplate technologies.
Glycosylation: The Sweeter Side of Proteomics
Technical Insight
Despite sample heterogeneity and complex enrichment methods, advanced MS solutions will drive the field of glycosylation into new and interesting territory.
MS-based Approaches for Ubiquitin Characterization
Technical Insight
Modern MS-based techniques aim to provide enhanced insights into the quantitative and qualitative features of ubiquitin and its multiple substrate pathways.
Protein Phosphorylation and Total MS Workflow Solutions
Technical Insight
Total MS workflow solutions have expanded the range of phosphoprotein analyses and the scope of proteomic investigations that can be explored.
The Journey from Biomarker Discovery to Validation to Clinical Implementation
Technical Insight
With a focus on mass spec methods and solutions, we explore the journey from biomarker discovery, to verification and validation, to clinical implementation.
LabX Industry Insights: Sample Delivery Systems for High Performance Liquid Chromatography and Mass Spectrometry
Technical Insight
Programmable high performance syringe pumps are utilized in MS and HPLC applications ranging from method development to instrument calibration
Tandem Mass Spectrometry Methods for Detecting Melamine and Other Adulterants in Food Items
Technical Insight
The scandals involving melamine as a food adulterant are valuable case studies as they have led to extensive research into analytical testing.
QuEChERS Extraction Modifications for Food Safety Testing
Technical Insight
MS methods for pesticide analysis have evolved over the years as many permutations of extraction, cleanup, separation, and detection have been implemented.
A Closer Look at Atmospheric Pressure Chemical Ionization (APCI) for Trace Compound Analysis
Technical Insight
APCI is a soft ionization technique that has proven ideal for fast screening of trace compounds, steroids, pesticides, food adulterants, and other analytes.
Compact Mass Spectrometers Offer Versatility for a Variety of Food Testing Applications
Technical Insight
In addition to food testing, portable compact mass spectrometry analysis is valuable in industries including food safety and testing, water purity, environmental sampling, and diagnostics.
Mass Spectrometry Testing Platforms for Food Safety Analysis
Technical Insight
With the growing variety of food sources and products available, there is a requirement for new technologies and testing methods to address safety concerns.
Cutting Mills for Cannabis Processing
Technical Insight
The ability to effectively mill cannabis, whether it be the stalks, stems, leaves, or flowers, depends on the performance and versatility of the device.
Certified Reference Materials and Internal Standards for Cannabinoid Analysis
Technical Insight
The quantitative power of analytical methods such as HPLC and LC-MS is often measured by the quality and performance of the reference standard.
Analysis of Cannabis Derived Terpenes
Technical Insight
As states continue to add terpene profiling to testing guidelines, accurate and precise methods for terpene analysis will become more and more important.
Pesticide Analysis in Cannabis using QuEChERS Extraction
Technical Insight
QuEChERS extraction is a reputable food and agriculture testing method that is now used by analytical labs for cannabis pesticides analysis.
Analytical Testing of Cannabis Consumables
Technical Insight
Accurate testing for the concentrations of cannabis compounds and pesticides is critically important in ensuring the safety of cannabis consumables.
MS User Pain Points Indicate a Greater Need for Instrument Efficiency and Workflow Optimization: Meet the Agilent Ultivo
Technical Insight
Agilent described a user-centric approach towards instrument and laboratory solutions development this year at ASMS.
The First FDA-cleared Vitamin D Assay Kit for Mass Spectrometry
Technical Insight
At this year's ASMS meeting, SCIEX shared a host of new developments including an exciting achievement in the clinical diagnostics field.
New Technologies Focus on Efficiency at ASMS 2017
Technical Insight
The 2017 American Society for Mass Spectrometry (ASMS) annual meeting highlighted many new transformative technologies, with a focus on efficiency.
Cannabis Science and Proposed Therapeutic Value
Technical Insight
As the industry grows and continues to mature, superior analytical methods and clinical standardization will undoubtedly be very closely linked.
8 Steps in Cannabis Processing and Analytical Testing
Technical Insight
There are vast opportunities for analytical laboratories in the processing, purification, potency testing, and quality control stages of cannabis production.
Quantitative Proteomics: The Difference a Generation Makes
Technical Insight
The latest advances in quantitative mass spectrometry and proteomics have expanded the footprint of research, as we discuss in the midst of the American Society for Mass Spectrometry annual conference.
Key Factors to Consider when Purchasing a New Cell Culture Incubator
Technical Insight
When looking for a new cell culture incubator there are a number of key factors you need to consider, from the types of cells to be incubated to the temperature and gas controls, as well as the adaptability of the device for future use.
What is a Limitation of Using Electron Microscopes to View Specimens?
Technical Insight
Electron Microscopy (EM) provides atomic level details into the structure of cells, tissues, and other specimens. Limitations are briefly discussed here.
Microscope Parts: Popular Components, Add-ons, and Replacement Parts for Brightfield and Fluorescence Microscopes
Technical Insight
The variety and functional significance of components, add-ons, and parts available for various microscopy platforms are briefly reviewed in this post.
Fluorescence Light Microscopy: Technical Insights and Applications
Technical Insight
Fluorescence microscopy is an essential tool in the biological and biomedical sciences, as well as other fields. Here we briefly discuss technical details and applications.
Brightfield Light Microscopy: Technical Insights and Applications
Technical Insight
Here we discuss technical details and applications of light microscopy, an essential technique used by many educational, diagnostic, and industrial research labs.
Laboratory Vacuum Pumps: Essential in everything from evaporation systems to high complexity analytical equipment
Technical Insight
Vacuum pumps are important components in lab equipment ranging from evaporation systems to mass spectrometers. Technical aspects are discussed in this post.
Evaporators: Type, size, and speed to match application, volume, and throughput
Technical Insight
The right evaporation system will provide reliability, functionality, and piece of mind to your research applications. Three of the main types are reviewed.
Mass Spectrometry Roundup: Ion Sources – Matrix-Assisted Laser Desorption Ionization (MALDI)
Technical Insight
MALDI is a powerful approach for analyzing difficult and large biomolecules. Discussed here is the MALDI ionization process and it's applications, strengths, and limitations.
Mass Spectrometry Roundup: Ion Sources – Electrospray Ionization (ESI)
Technical Insight
This summary on electrospray ionization (ESI) offers technical information to identify ion sources best suited for biological, clinical, or other applications.
How to Know Your Liquid Chromatography Pumps Need Service or Replacement
Technical Insight
This article details the troubleshooting process for high performance liquid chromatography (HPLC) pumps, with suggestions for service or upgrades.
How to Know it’s Time to Replace Your HPLC Column
Technical Insight
What to look for in proper HPLC function as well as suggestions for troubleshooting, repair, and upgrades are discussed.
HPLC versus UHPLC: An evolutionary step to address speed versus resolution
Technical Insight
This article explores the key differences between HLPC and UHLPC, with information on how each technology is best applied in the research setting.
FPLC versus HPLC: Two divergent separation technologies with a common ancestor
Technical Insight
The background and technical details of HPLC in comparison with FPLC are discussed, with a focus on defining suitability for specific research applications.
Vortex Mixers: Essential devices for clinical, research, and analytical lab sample processing
Technical Insight
Vortex mixers are a fixture in many labs. Practical considerations regarding features, purchasing decisions, and specific products are detailed in this article.
Parafilm: A ubiquitous laboratory staple with an interesting array of uses
Technical Insight
<p>Parafilm is a mainstay in the laboratory that has an interesting background and diverse array of uses beyond the typical.</p>
KimWipes: A variety of product types for a wide range of applications
Technical Insight
KimWipes are a must have for most laboratories, and the KimTech brand includes many additional products and applications offering not just popularity but versatility.
Nanodrop: A shift in DNA/RNA/Protein quantitation
Technical Insight
This article provides an overview of the Nanodrop technology used in nucleic acid and protein quantitation, with a focus on technology and functionality.
Mass Spectrometry Roundup: Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Technical Insight
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) is a widely used technique. Practical and technical considerations are summarized in this article.
The Advantages and Disadvantages of Specific Mass Spectrometry Platforms
Technical Insight
The are many types and configurations of mass spectrometers. This article summarizes strengths and limitations of commonly used mass analyzers.
Mass Spectrometry Roundup: Mass Analyzers – Time-of-Flight (TOF)
Technical Insight
Time-of-Flight (TOF) mass analyzers are most commonly coupled with MALDI sources in biological applications. Here the technology is discussed.
Mass Spectrometry Roundup: Mass Analyzers – Quadrupoles
Technical Insight
There are many uses for quadrupole mass spectrometers in biological and clinical settings among others. A brief summary of technical and practical considerations is offered.
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