Driving the Field of Oligonucleotide Therapeutics: eBook
Written By: Damon Anderson, PhD
Feb 07, 2024
State-of-the-art solutions for oligonucleotide characterization, purification, and manufacturing
The research and development of oligonucleotides represents a revolutionary approach to discovering new and important therapeutic agents. There are challenges, however, in the synthesis, purification, and large-scale production of oligonucleotides. These challenges must be overcome to realize their true therapeutic potential.
Analytical testing solutions are essential in driving
research to confidently identify and validate new therapeutic candidates. These
analytical solutions include raw/starting material analysis for oligonucleotide
synthesis, purity analysis, sequence confirmation, and purification techniques to
support validation and quality control for downstream applications. Preparative
solutions are necessary to enable oligonucleotide production and scale-up to
manufacturing.
This eBook highlights the associated complexities of oligonucleotide synthesis and the range of technologies designed to streamline and advance oligonucleotide characterization, purification, and scale-up to production.
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