Used vs. Certified Pre-Owned Liquid Handlers: Know Before You Buy

Essential considerations for ensuring the right solution for your lab

Whether you’re running high-throughput screening, genomic assays, or routine sample prep. automated liquid handling systems are a backbone of modern labs.  These instruments save time, reduce human error, and support reproducibility. But new liquid handlers can be expensive, and many labs turn to the secondary market to expand their automation capacity. The big question that surfaces is whether you should you buy used or certified pre-owned (CPO)?

Used Liquid Handlers: Lower Cost, Higher Risk

Buying a used liquid handler typically means acquiring an instrument “as-is” from a reseller, auction, or another lab.

Certified Pre-Owned Liquid Handlers: Validated and Reliable

CPO liquid handlers undergo a rigorous refurbishment process before resale.

ROI: Why the Difference Matters

Used systems may look appealing for cost savings but can quickly erode ROI if they fail during critical runs or require major repairs. In fields like genomics, drug discovery, or clinical research, downtime can delay results and increase costs.

CPO systems, on the other hand, deliver a stronger ROI because:

  • They arrive ready to integrate into workflows

  • They minimize downtime and service costs

  • They extend the operational lifespan of the investment

  • They provide documentation that helps avoid compliance setbacks

Which option Is right for your lab?

Download the Buyer's Guide to Certified Pre-Owned Liquid Handlers to learn the truth about CPO equipment and what sellers don't tell you.